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(Lab Study)
Rapid fat loss, particularly from the face and neck, can accelerate the appearance of skin laxity
The gut lining can take a beating during extended use of GLP-1 class medications, and some researchers believe that supporting gut integrity proactively leads to better long-term tolerance
Obesity trials use weight as the primary endpoint
Some medications and supplements can cause even more profound changes: Bright orange : May result from rifampin or phenazopyridine Blue or green : Possible side effects of medications like amitriptyline or propofol Dark brown : Can occur with antimalarials or laxatives According to the Mayo Clinic (2022), medications and supplements frequently alter urine color and should be considered before assuming a medical concern [Mayo Clinic]
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