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[9] A separate small multicenter Phase II trial (registered as NCT01393132) in patients with severe dry eye reported significant improvements in both signs and symptoms versus vehicle control

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The combination of 2.4 mg/week cagrilintide with semaglutide led to the most significant weight loss (-17.1% from baseline), and both the 2.4 and 4.5 mg/week doses showed an identical placebo-adjusted weight reduction of -7.4% [10]

Tardivo et al