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The mitochondrial apoptosis-inducing factor plays a role in E2F-1-induced apoptosis in human colon cancer cells

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Reduces oxidative stress As the mother of all antioxidants, glutathione fights free radicals and reduces oxidative stress

Targeting different sites involved in caspase interactions with XIAP using small-molecule chemical inhibitors induces synergistic apoptosis of leukemia cells

doi: 10.3748/wjg.v20.i25.8082 66

Senapati J, Ishizawa J, Abbas HA, Loghavi S, Borthakur G, Issa GC, Dara KI, Pourebrahim R, Daver N, Jabbour EJ, Kornblau SM, Pemmaraju N, Garcia-Manero G, Ravandi F, Muftuoglu M, Khoury J, DiNardo C, Andreeff M