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The STEP 4 trial demonstrated that continuous weekly dosing was necessary to maintain weight loss, and discontinuation resulted in weight regain
3) Dont undereat by accident If youre living on yogurt, half a salad, and coffee, the scale may drop, but your energy, strength, and mood will drop too
These numbers also match what we see in clinic: shedding tends to appear in people with large calorie drops, not in those maintaining balanced intake and steady progress
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Weight loss, insulin sensitivity, metabolism, and body fat all play a role in reproductive hormone balance
Real-Life Experience: Tirzepatide vs Semaglutide Side Effects Beyond clinical lists, many people notice: reduced hunger between meals smaller portion sizes occasional fatigue early on sensitivity to heavy meals Hydration, meal timing, and protein intake often make a noticeable difference in daily comfort
