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These flexible regions allow multiple conformational states depending on environmental conditions

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Cell Discov 9(1):92 Li Z, Gu Z, Wang L, Guan Y, Lyu Y, Zhang J, Wang Y, Wang X, Xiong J, Liu Y (2023c) Nuclear translocation of ldha promotes the catabolism of bcaas to sustain gbm cell proliferation through the txn antioxidant pathway

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All of which are often missing in mainstream discourse