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Semaglutide is a medication, typically administered through at-home injections one-time per week, that aids in weight loss

Semaglutide is not always effective for everyone, but when successful, it can make a difference of up to 15% in body weight

In clinical trials of Zepbound, about 7% of people on 15 mg, 6% on 10 mg, and 5% on 5 mg reported fatigue, versus 3% on placebo

For patients concerned about blood sugar management, pairing rice with protein (like chicken or beans) and vegetables creates a more balanced meal that maximizes satiety and minimizes glucose fluctuations

General hydration guidance, not a GLP-1-specific rule, is the place to start, and your doctor can tailor it

Any significant weight loss, regardless of method, results in some lean mass loss