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In diabetic mice, 50 mg/kg body weight/day oral doses of arginine reduced AGE formation in glomerular basement membrane collagen (93)

This form encapsulates glutathione molecules within tiny phospholipid bubbles, essentially creating microscopic protective spheres that can survive the harsh acidic environment of the stomach and pass through intestinal walls intact

Dosing interval : 46 hours apart to optimize absorption peaks

Trial-Reported Endpoints by Phase Trial Lancet 2021 Phase 2 Duration 26 weeks Population Overweight/obese, no T2D (n=706) Mean Weight Loss 10.8% at 4.5 mg vs 3.0% placebo Trial Lancet 2023 Phase 2 Duration 32 weeks Population T2D + obesity (n=92) Mean Weight Loss 8.1% cagrilintide alone

Introduce new products slowly and at intervals to avoid any source of irritation

Watkins, Marcus