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The pathophysiology of DDES is complex, involving lacrimal gland mitochondrial dysfunction, neuro-inflammation, ocular surface dysbiosis, and meibomian gland dropout [122,123,124]
GLP-1 and GIP/GLP-1 medications have boxed warnings regarding thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2) and carry risks of pancreatitis, gallbladder disease, and diabetic retinopathy progression
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What the Research Says About Akkermansia Muciniphila and Inulin The brand describes Akkermansia muciniphila and artichoke-derived inulin as compounds studied in connection with gut and metabolic pathways, and that part of the marketing isn't invented - both are genuinely active subjects in gut-microbiome research
They increase glucose uptake and utilization and improve cardiac metabolism, as well as left ventricular function36,41
