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If nausea or constipation persist after 2 weeks of dietary adjustments and movement, your provider may recommend pausing dose increases, temporarily reducing your current dose, or switching to an alternative GLP-1 compound

In: Sparks DL, editor

It reduces glucagon release from the pancreas

The committee concluded that cannabis use typically has negative effects on mental health, increasing the risk of developing schizophrenia and social anxiety disorders and worsening symptoms in people with bipolar disorder

Neuroimmunomodulation 2011

While it is a possible alternative, the statistics implied that Trulicity has better adherence, longer persistence and lower discontinuation rates compared to Byetta