Loss of function mutations in IGSF1 result in a variable spectrum of anterior pituitary dysfunction, including central hypothyroidism and hypoprolactinemia (384,385)
(PubMed) DeLong GR, Leslie PW, Wang SH, et al
GLP-1 RAs are also contraindicated in patients with personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2, which requires clinical awareness [,]
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Accordingly, the anti-inflammatory mechanisms associated with GLP-1RA treatment could be closely linked to the cardiovascular benefit seen in clinical trials (5154)
324 The Behavioral Risk Factor Surveillance System survey, a large crosssectional, telephonebased survey of communitydwelling people across the U.S