FIGURE 2 3.1 Brain insulin resistance Insulin resistance in the brain perpetuates neuroinflammation, tau hyperphosphorylation, and amyloid pathology in AD and is therefore a driver of neurodegenerative disease (Hlscher, 2019)
Adv Ther 39(6):24522467
doi: 10.1038/s42255-023-00811-0
Have contraindications for GLP-1 medications: If you have personal or family history of medullary thyroid carcinoma, MEN 2 syndrome, or other contraindications, GLP-1 medications are not appropriate regardless of the access pathway
Combining Preparations for easier administration and improved compliance For example: A patient's provider finds their lab results to be low in Estradiol, Progesterone and Testosterone
CJC-1295 with DAC carries a Drug Affinity Complex that binds it to albumin, extending half-life to 5.8-8.1 days (Teichman 2006, JCEM)