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GLP-1 receptor agonists play a crucial role in improving insulin sensitivity for women with PCOS by encouraging the release of insulin in response to glucose levels

In Vikings Phase 2 VENTURE Oral trial, at the 13-week primary endpoint, patients receiving the 120 mg top dose achieved a mean weight loss of 12.2% (10.9% placebo-adjusted), but this was marred by a 38% discontinuation rate, nearly double the 18% seen in the placebo arm and leaving a net 20% discontinuation rate

Recognizing the Signs of Medication Overload If you have mistakenly taken more than one GLP-1 medication or took too high a dose, it is important to recognize the warning signs of overload. You should seek medical attention immediately if you experience: Severe, persistent abdominal pain that radiates to your back

The Specialist Pharmacy Service (UK) advises switching to a GLP-1 receptor agonist rather than adding a DPP-4 inhibitor like Januvia when intensifying therapy

A consult can also sort whether your main driver is collagen loss, pigment, laxity, or a mix

This page is for informational purposes only and should not be used to replace a medical opinion