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This was already revolutionary, as previous products like Ozempic worked with only one receptor

At the end of the trial, compared to the group taking sulfonylureas, participants who consistently took GLP-1 medications for the entire three-year period of the study had the most pronounced reduction in risk 18%, or roughly 4 fewer major cardiovascular events per 100 people over three years

95% CI, 0.56 to 0.84) (eTable 3)

Freo U, Furnari M, Ambrosio F, et al

According to research published in Diabetes, Obesity and Metabolism, semaglutide reduces appetite by acting on areas of the brain responsible for regulating food intake

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