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Assessing the Association Between GLP-1 Receptor Agonist Use and Diabetic Retinopathy Through the FDA Adverse Event Reporting System

Biochemical analysis of the lipoprotein lipase truncation variant, LPL(S447X), reveals increased lipoprotein uptake

Sensitivity analyses showed that the probability of using GLP-1RAs versus insulin being cost-effective for preventing one case of all-cause mortality or hospitalized hypoglycemia ranged from 60 to 100%

That means a 250mcg dose is only 2.5 units nearly impossible to measure accurately on an insulin syringe

While it looks at a very different (and more severe) health risk, the study is similar to Ozempics case in the sense that both aim to balance the trade-off between treating new and existing patients under supply uncertainty

The symptoms in patients are severe and often accompanied by functional impairments, especially in the obese population