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PTK2 signaling upholds the transcription and translation of pro-inflammatory signaling molecules majorly TNF-, IL-1, and some cell adhesion molecules involved in inflammatory responses (Murphy et al., 2019)

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Now, it comprises 8.9% of the global analgesics market with a market value of $9.8 billion [14]

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This suggests the physiological importance of the ZIP13-C/EBP- axis in beige adipocyte biogenesis and thermogenesis, and also highlights its potential in obesity treatment