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Significant weight loss potential: Early studies suggest it may surpass existing pharmacological options in terms of weight reduction magnitude

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Since then, the evolution of GLP-1 receptor agonists has progressed from initial short-duration agents like exenatide, to intermediate-duration formulations such as liraglutide, and further to advanced long-acting options including dulaglutide and semaglutide (The two products received approval for marketing in the U.S

age 48 8, BMI 29.9 4.4, 2.6 1.0 years post-RYGB), and 8 overweight/obese individuals without T2D and without history of gastrointestinal surgery (Ow/Ob) (5 female, 2 male