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Nutr Metab Cardiovasc Dis 20(1):7277 Ogawa D, Asanuma M, Miyazaki I, Tachibana H, Wada J, Sogawa N, Sugaya T, Kitamura S, Maeshima Y, Shikata K (2011) High glucose increases metallothionein expression in renal proximal tubular epithelial cells

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253 Metabolomic studies have also revealed how polyphenols like CGA influence gut health through microbial metabolites such as glycine-rich extracellular vesicles, which suppress NF-B signaling and reduce inflammation