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Scientists had to synthesize the 39-amino-acid peptide in quantities sufficient for clinical trials, formulate it for injection, and demonstrate safety and efficacy in thousands of patients

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Benefits of rotating injection sites include: Reduced skin irritation Improved comfort Reduced scar tissue formation Better long-term injection tolerance Many patients rotate between the abdomen, thighs, upper arms, and glute area throughout treatment

doi: 10.1073/pnas.0900977106

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