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Tyrosinase-related protein 1 stabilizes the enzyme tyrosinase and is involved in melanosome maturation, and tyrosinase-related protein 2 modulates the quantity and quality of the melanin produced

BCBS MA ultimately removed weight management coverage for fully insured plans while allowing large employers to purchase supplemental riders

Patients who successfully implement and sustain meaningful dietary changes, regular physical activity, and behavioural strategies may have better outcomes if treatment is reduced or stopped

Set realistic expectations Results vary by person, medication, dose, and starting point

Eating greasy, fried, spicy, or very sugary foods may irritate the stomach further

PMID 8112494