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4HNE conjugates with cell proteins and this effect can be visualized by Western blotting with an anti-4HNE antibody 42

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As depicted in Figure 1, dipeptidylpeptidase-4 (DPP-4) is an ubiquitously expressed transmembrane protein that removes N-terminal dipeptides from various substrate hormones, chemokines, neuropeptides and growth factors

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