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Prevalence of the deficiency is correlated with the geographic distribution of malaria, which has led to the theory that carriers of G6PD deficiency may incur partial protection against malarial infection

In contrast, the difference in liver fibrosis resolution stage did not reach statistical significance (liver fibrosis staging improved in 43% of participants in the semaglutide arm vs 33% in the placebo arm), potentially owing to a lack of power within the study or the relatively short follow-up time of 72 weeks

One hypothesized mechanism for these potential protective actions against liver cell fibrosis might involve the modulation of matrix metalloproteinase (MMP) activity and the suppression of tissue inhibitors of MMPs (TIMPs)

Son yllarda zellikle kilo ynetimi, inslin direnci ve tip 2 diyabet srelerinde daha sk gndeme gelmeye balamtr