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Managing Potential Side Effects Some people on GLP-1s may experience gastrointestinal symptoms such as nausea, constipation, or diarrhoea - especially in the early weeks of treatment

Prebiotics can be used to promote metabolic health and longevity by stimulating intestinal production of GLP-1, and so too can the drug Acarbose, which acts as a starch blocker, inhibiting the enzymes that would normally digest carbohydrates earlier in the small intestine

Bottom line: Treatment should be individualised according to patient goals, comorbidities, and adherence potential