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doi:10.1007/978-1-4939-8910-2_20
The GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) and the GIP/GLP-1 dual agonist tirzepatide sit behind the STEP (NEJM, 2021), SURMOUNT (NEJM, 2022), and SURMOUNT-OSA (NEJM, 2024) evidence, and the clinical picture does not change with the price tag
Most adults enter weight loss with some degree of insulin resistance from years of eating a standard high-carbohydrate diet
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