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Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, et al

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Thus, regardless of our understanding of the physiology or pathophysiology of islet produced GLP-1, these data suggest that this pool of GLP-1 could be targeted to treat T2DM and avoid some of the CNS side-effects (i.e., nausea) associated with long-acting GLP-1 agonists