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Part 2: The Small-Molecule Battlefield Hatch-Waxmans Rules of War Key Takeaways: Part 2 The Drug Price Competition and Patent Term Restoration Act of 1984 (Hatch-Waxman Act) created a deliberate, bilateral system of incentives designed to produce generic competition while protecting brand innovation, and it has worked: generics now account for over 90% of U.S

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To establish whether differences in binding affinity could contribute to the elevated GLP-1 levels in PAM T2D-risk allele carriers we measured receptor binding affinity in competition with 125 I-GLP-1(736 amide) for both the amidated and non-amidated forms of GLP-1 demonstrating that they are equipotent (Additional file 2: Fig