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In fact, treatment with NAC in normal rats effectively reduced ROS levels in chondrocytes and Lin CD45 + AnV marrow cells [27], suggesting that in our model, the antioxidant therapy probably reduces intracellular ROS content in the adrenal and pituitary glands

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Options include partial reconstitution (if feasible with your vial format), freezing portions of reconstituted solution (accepting some potency loss), or adjusting your dose higher to use everything before expiration