AOP Development Strategy Context This AOP was developed for the project "CHRONIC TOXICITY OF PESTICIDES IN DRINKING WATER IN PARABA (TRIGGER): IDENTIFYING THE TRIGGERS OF A SILENT EPIDEMIC," financed by the "Fundao de Apoio Pesquisa do Estado da Paraba (FAPESQ-PB)." The project aims to understand how oxidative stress and reproductive toxicity can be triggered in animals by aquatic pollutants, such as atrazine Strategy The first step in developing this AOP was to conduct a literature review to gather toxicological data on the herbicide atrazine's impact on aquatic vertebrates in relation to oxidative stress and reproductive toxicity
If you notice bloating, lower the dose to determine if the side effects go away
Antioxidant Supplement with L-Glutathione: Each antioxidant tablet is designed to support the maintenance of glutathione levels already within a healthy range
Also, the expression of Bone Morphogenetic Protein 7 (BMP7), a transforming growth factor (TGF-) superfamily that can induce BAT adipogenesis and increase UCP1 expression, was measured
Methods Biochem
Each capsule delivers 500 mg of reduced glutathione alongside milk thistle extract (silymarin, which supports liver function and has been shown in research to help maintain glutathione levels) and alpha lipoic acid (a potent antioxidant that helps recycle both glutathione and vitamins C and E back to their active forms)
