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However, they are most effective and safest when used for their approved purposesprimarily for people with obesity or type 2 diabetes

Herman, 2003

Intranasal deferoxamine provides increased brain exposure and significant protection in rat ischemic stroke

Insurers in some markets are facing mounting market pressure to remove the exclusion on weight management to promote inclusivity, resulting in the imminent exposure of insurers in these markets to reimbursement of this class of drugs

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However, in prediabetes and diabetes, this signal is blunted by insulin resistance in the liver