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This compound is handled exclusively in controlled research settings for in vitro and pre-clinical studies, with no applications in human or veterinary medicine

The mean absolute bioavailability observed after IM injections was approximately 14%19% in rats and 45%51% in beagle dogs

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Thigh For intramuscular injections, the center of the top of the thigh is a smart place to choose since the muscle there is easily accessible

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Methotrexate was continued through the course of the trial, and the clinical response was the same in patients with or without concomitant methotrexate use (Figure 7-12)