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Strikingly, estrogen deprivation was shown to be the principal mediator of impaired wound healing in the elderly population when a microarray study revealed that 78% of genes differentially expressed between wounds from young and aged men were estrogen-regulated, while only 3% were related to intrinsic aging (Thornton, 2013)

Clinical and demographic dataincluding age, sex, BMI, duration of diabetes, smoking status, comorbidities, laboratory values, and current medicationswere collected from electronic medical records

Appointment length: 30 to 45 minutes

Thus, this case of acromegaly supports our hypothesis that GLP-1 analogs are more effective than DPP-4 inhibitors for pasireotide-induced hyperglycemia

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When compared to dulaglutide and placebo, tirzepatide statistically significantly displayed improvement in ALT and AST from baseline