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A meta-analysis of observational studies (1561 women with pre-existing diabetes and GDM) found that lispro compared to regular insulin was associated with decreased rates of severe maternal hypoglycemia and neonatal jaundice, but increased rates of LGA infants (135)

New insight into glucose metabolism dysregulation in TBI Current consensus suggests that primary TBI immediately resulting from mechanical stress and displacement of brain tissues is compounded by progressive secondary injury (damage to the BBB, protein aggregation, etc.) that is partially mediated by metabolic dysfunction [27]

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