Potential side effects of semaglutide include: nausea and vomiting diarrhea and constipation stomach pain fatigue hypoglycemia (low blood sugar) acute kidney injury injection-site reactions to injected versions of the drug Overall, semaglutide is also linked to an And its important to remember that when semaglutide is combined with other drugs, additional side effects may occur
For a complete explanation of how semaglutide works, dosing schedules, expected results, and who qualifies, see the full semaglutide 2026 guide
Glucagon receptor Glucagon is traditionally associated with raising blood glucose by stimulating hepatic glucose output
GLP-1 regulates hunger and blood sugar levels after you eat food
The top dose is not the goal
After your first dose, semaglutide begins mimicking GLP-1 , a hormone that helps regulate appetite and blood sugar