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Front Immunol (2019) 10:3099

For instance, identifying loss-of-function mutations in the IL-36Ra gene has led to developing IL-36 inhibitors for patients with GPP (Johnston et al

Our experience shows that starting on the lower end of the spectrum is almost always the wisest approach

But research shows that smaller peptides, especially when paired with delivery systems or used in leave-on products, can reach the deeper layers where theyre needed most

Lundgaard Donovan L, et al