VBDS has a variable clinical course, from full liver recovery and reversibility to prolonged bile duct loss [64]
Horses with higher protein or calorie needs, such as growing horses, broodmares, or those on lower-quality forage, may benefit from the addition of a protein source like soybean meal or alfalfa pellets
Some signs and symptoms are only described in a few case reports, and include peripheral neuropathy involving both upper and lower limbs, mild developmental delay, anemia, respiratory distress and proximal muscle weakness [65,66,67]
Walsh, T
Mast cell activation generates reactive oxygen species and perpetuates oxidative damage
This effect is mediated by a reduction in the synthesis of prostaglandins, which are cell-signaling molecules derived from the omega-6 fatty acid arachidonic acid via the action of the cyclooxygenase enzymes (Downie 1991