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among the latter, in patients who were responsive (effective group) and non-responsive (ineffective group) after 2 weeks of treatment

Black KL, Baba T, Pardridge WM

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FTH neuron-specific knockout (FTH-KO) mice are more susceptible to ferroptosis after TBI, and the absence of FTH offsets the protective effect of melatonin on ferroptosis induced by TBI, 659 suggesting that melatonin plays a protective role at least in part by inhibiting FTH-mediated ferroptosis in neurons after TBI