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Lipid droplets are encapsulated by a unique phospholipid bilayer that is often continuous with the outer leaflet of the ER membrane, which sets them apart from canonical MCSs

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Two plateaus are seen for glycine as it has two ionizable groups (protonated amine and carboxylic acid)

This dual role, known as antagonistic pleiotropy, beneficially suppresses tumor initiation early in life but detrimentally increases the risk of age-related pathologies, later

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