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Medical concepts are systematically categorized using the Medical Dictionary for Regulatory Activities (MedDRA) terminology, with Preferred Terms (PTs) representing granular AE descriptions, hierarchically grouped into High-Level Terms (HLTs), High-Level Group Terms (HLGTs), and System Organ Classes (SOCs) 18,19

This signaling stimulates calcitonin release from the cells and promotes cellular proliferation

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Sensitivity to mechanical stress Tirzepatide, like all larger peptides, is more susceptible to denaturation from mechanical stress (shaking, vigorous mixing) than smaller peptides