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Neutrophil activation and adhesion to endothelial cells amplify the inflammatory response, resulting in endothelial dysfunction and exacerbating tissue injury [8]

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And according to a systematic review and meta-analysis published in Obesity Reviews , people who stopped GLP-1 therapy regained an average of 2.2 kg when coming off liraglutide and 9.7 kg when discontinuing semaglutide or tirzepatide

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