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People who use peptides for two weeks, feel some pain relief, and stop often find the pain returns because the underlying tissue has not had time to fully remodel

Leah Joseph, MD, FACP , provides expert care with GLP-1 medications for weight management and metabolic health

Last updated July 16, 2026

The Journal of nutrition

The stabilization level depends heavily on whether treatment created structural dermal improvements supporting ongoing collagen synthesis or merely provided temporary stimulation requiring continuous application

Theres a huge distrust of mainstream medicine now, so not being a doctor probably actually does him favors, she says