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However, in Listeria monocytogenes the gpoA mutant showed improved oxidative stress resistance and pathogenicity using a mice model [14]

Notably, it has been reported that the gut microbes could metabolise tryptophan into tryptamine, kynurenine and indole derivatives involving the indoleamine 2,3-dioxygenase 1 (IDO1) and aryl hydrocarbon receptor (AHR) that have crucial roles in the immune homeostasis and tumour immune microenvironment respectively [247,248,249,250,251]

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The recommended daily intake (RDI) of vitamin B12 for adults over 19 is Deficiency is common, especially in people who follow a vegetarian or vegan diet

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33 The clinical efficacy of SAM in the treatment of cholestasis associated with hepatic diseases has been reviewed