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The pigment deposits replicate hair follicles and create the appearance of a full head of hair
In late August 2015, the US FDA issued a warning that drugs like sitagliptin, saxagliptin, linagliptin, alogliptin, and other DPP-4 inhibitors could cause joint pain that can be severe and disabling
Additionally, anyone with a history of pancreatitis or severe gallbladder disease may need to avoid this medication due to GLP-1 receptor activity in those tissues
Individual responses can vary, and some patients may experience a gradual increase in appetite suppression during the dose-escalation phase