Unlike the SUSTAIN-6 study, this study excluded any patients who had pre-existing proliferative diabetic retinopathy (PDR) prior to initiation of tirzepatide and matched patients with their baseline level of DR or DME
Whilst transdermal patch delivery systems are being explored in research, it is crucial to understand that no GLP-1 patches are currently licensed or approved for use in the UK
We searched PubMed, Web of Science, and Embase from inception through April 2025 using the terms GLP-1 receptor agonists, GLP-1RAs, neurodegeneration, Alzheimer's, Parkinson's, multiple sclerosis, ALS, mechanisms, clinical trials, and biomarkers. Studies were included if they were English-language, peer-reviewed, and focused on central nervous system effects
Cell-attached patch recordings revealed that the external bath application of 10 nM CAP and 100 nM exendin 939 did not reduce the frequency of single-channel open events
Taking progress photos is another great way to visually document your journey
Current evidence shows no increased pancreatic cancer risk with GLP-1 medications