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Patients enrolled in the trial had biopsy proven NASH/borderline NASH (NAS 4) without cirrhosis (n = 283)
Additionally, liraglutide prevented macrophage migration
doi: 10.1523/JNEUROSCI.2105-10.2010, 140 SticeE.YokumS.BohonC.MartiN.SmolenA
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To get the two peptides to co-formulate in a single injection device with both equally optimum dosages while ensuring compatibility between them and stability during storage, advanced pharmaceutical development was required for co-formulation of cagrilintide with semaglutide in CagriSema
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