One of the most important variables in the model, ATP concentration, was reported as being 2 mM in many experimental and modeling studies (60, 80)
doi: 10.3390/vaccines9101108 Pubmed Abstract CrossRef Google Scholar View reference in article 61 LeeKAKimYJJinHY
The differences in function between type A and type B intercalated cells is due, in part, to the opposing distributions of various transporter proteins which, for example, places a particular transporter in the apical membrane of a type A cell and the same transporter in the basolateral membrane of a type B cell
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The nonenzymatic initial reaction between 1 M roGFP2 WT (S 2 ) and physiological millimolar GSH concentrations was too slow to be detectable and to be of any relevance in the presence of glutaredoxins in accordance with previous analyses 32
These findings have important clinical ramifications with the possibility of targeting ferroptosis pathway in GPX4-overexpressing thyroid cancers