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Importantly, ipamorelin appears to augment the natural pulsatile pattern of GH release rather than producing a sustained, non-physiological elevation

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It also regulates the activity of microglia in the brain, which are responsible for scavenging dead neurons and any foreign invaders

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[6] This interaction is hypothesized to trigger a cascade of intracellular signaling mechanisms

Ipamorelin is a highly selective pentapeptide growth hormone secretagogue that activates the GHSR-1a (ghrelin receptor) without significantly influencing other pituitary hormones