no weight loss semaglutide Could a pill help with loss? Woman shares journey of weight

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A study published in PubMed showed that semaglutide itself reduced neuropathic pain markers in diabetic animal models through mechanisms involving reduced spinal cord inflammation

In pivotal trials, weekly semaglutide produced roughly 1415% body-weight reduction at 68 weeks (STEP 1, NEJM 2021), and tirzepatide a dual GIP/GLP-1 co-agonist reached 1822% at one year (SURMOUNT-1, NEJM 2022)

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