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Both drugs carry a black box warning for thyroid C-cell tumors, although this has primarily been observed in animal studies

[1] [2] Unlike phentermine's central nervous system stimulation, tirzepatide works through multiple mechanisms: it enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through central pathways

However, this should still be mentioned at your next scheduled appointment

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What Are the Real Safety Risks with Compounded Tirzepatide

Regulators contacted over 13,500 people about their potential exposure