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At full retail, tirzepatide runs modestly higher than semaglutide across comparable indications, though the gap has narrowed as Zepbounds pricing has been positioned more competitively than Wegovys

With the prevalence of glucagon-like peptide-1 (GLP-1) drugs, more individuals are recognizing obesity for what it is: a chronic disease, rather than a condition caused by a lack of willpower

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By contrast, the STEP 4 study did not show a clear slowing of weight regain towards the end of its 48week observation period following semaglutide withdrawal

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