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JACC Heart Fail 7(5):383391

doi: 10.1007/s10557-025-07670-9, 56

This is an important discovery that identified the long-sought-after incretin (an intestine-secreted hormone that triggers insulin release) and led to its application as an anti-diabetic strategy

In particular, they can be subdivided in general transcription factors

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Studies have shown that significant concentrations of lixisenatide were found in the brain of mice 30 minutes and 3 hours after intraperitoneal injection, suggesting that lixisenatide could cross the BBB (125)