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Tirzepatide, a dual GIP/GLP-1 receptor agonist, may also offer more favorable muscle preservation profiles, although further studies are needed

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A recent review found that patients using GLP-1 medications may be at increased risk for 19: Low protein intake Reduced intake of key micronutrients like vitamin D, iron, and calcium Declines in vitamin B12 and thiamine (B1) over time In some cases, this may contribute to: Fatigue or low energy Loss of lean muscle mass Longer-term nutrient deficiencies, if not addressed This is not a reason to avoid these medications, but it does highlight the importance of dietary quality and intentional nutrition support from a qualified professional while using them

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2020Nov 1;10(11):222745